SOP on Cleaning of Dry Syrup Filling Machine

SOP on Cleaning of Dry Syrup Filling Machine



Objective : To describe a cleaning procedure for the dry syrup filling machine.


Scope : To ensure that the equipment is clean and free from any starting materials of previous batch or product residues.


Responsibility : 1.It  is the responsibility of operating staff to clean the equipment.

2. Production Chemist to ensure that procedure is followed.


Materials & Equipment :

1.      Cleaning agent: Teepol or liquid soap.

2.      Mops / brush / lint free cloth




(1)   Remove visible material from the machine with the help of a jet of compressed air.

(2)   Dismantle the hopper, nozzle etc. and place in a plastic tub.

(3)   Take the dismantled parts to washing area and clean them with 10 liters of boiled tap water and drain the washings.

(4)   Prepare a Teepol solution (10ml à 10 liters water) or liquid soap (50gm à 5 liters water) and clean the surfaces of all the dismantled parts by mopping.

(5)   Wash all the dismantled parts by running tap water for 5 minutes.

(6)   Wash all the dismantled parts with 5 liters of purified water.

(7)   Finally rinse all the parts with previously boiled purified water and drain it completely.

(8)   Send the wash water for analysis of residual active ingredients of previous product.

(9)   Let all the machine parts dry in air or dry with a clean lint free cloth, reassemble in the reverse order of dismantling and put a label “Clean” or “Ready for use”.


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