SOP on Cleaning of Octagonal Mixer

SOP on Cleaning of Octagonal Mixer

 

 

Objective: To describe a cleaning procedure for Octagonal Mixer.

 

Scope : To ensure that the equipment is clean and free from any starting materials of previous batch or product residues.

 

Responsibility : 1.It  is the responsibility of operating staff to clean the equipment.

2. Production Chemist to ensure that procedure is followed.

 

Materials & Equipment:

1.      Cleaning agent: Teepol or liquid soap.

 

Procedure

(1)   Switch ‘OFF’ the mains of machine.

(2)   By inching bring the machine in such a position that bolts of the lid can be open.

(3)   Open the bolts & lid and clean any visible material from the machine with the help of a dry lint free cloth.

(4)   Add about 15lts. of tap water, close the lid and tight the bolts. Run the machine for 10minutes.

(5)   Again open the bolts & lid, and drain out the water. Clean octagonal mixer with a wet lint free cloth and remove any visible material .

(6)   Repeat the step no. (4) first with 15lts.tap water and then with 5lts. DM water

(7)   For colured powders or potent drugs, first remove any visible material from the machine with the help of a wet mop. Then add 15lts of teepol or detergent solution and repeat the step nos. 4 to 6.

(8)   Send the wash water for analysis of residual active ingredients of previous product.

(9)   Allow the machine to dry in air.

(10)           Put a label “cleaned” or “ready for use”.

 

 

Reason for Review: Minor revisions in format.