SOP on Cleaning of Blister Strip Packing Machine

SOP on Cleaning of Blister Strip Packing Machine


1.0 Objective : To describe the cleaning procedure for blister strip packing machine. 


2.0 Scope : To ensure that the equipment is clean and free from any starting materials of previous batch or product residues.

3.0 Responsibility : 
1.It  is the responsibility of operating staff to clean the equipment.
2. Production Chemist to ensure that procedure is followed.


4.0 Materials & Equipment :
1. Cleaning agent: Teepol or liquid soap / Isopropyl alcohol
2. Mops / brush / lint free cloth


5.0 Procedure 

5.1 At the end of day or product change-over remove any visible material from the machine with the help of a jet of compressed air. 
5.2 Dismantle the hopper, feeding tray, channels etc. and keep the parts in a plastic tub containing 5 liters of boiled tap water. 
5.3 Remove any visible material from the surfaces of all the dismantled parts with the help of nylon brush or scrubber and drain the washings. 
5.4 Prepare a Teepol solution (10ml  10 liters water) or liquid-soap (50gm  5 liters water) and clean the surfaces of dismantled parts by mopping. 
5.5 Wash all the dismantled parts with running tap water for 10 minutes and drain the washings. 
5.6 Wash all the dismantled parts with 10 liters of purified water, then rinsed with previously boiled purified water and drain it completely. Let the dismantled parts air-dry or dry with a clean lint free cloth. 
5.7 The rollers are dismantled and wiped with 70% v/v Isopropyl alcohol. 
5.8 All used rubber stereos are destroyed. 
5.9 Conveyor belt of the machine is cleaned with 70% v/v Isopropyl alcohol. 
5.10 After completion of cleaning work, and authorization from QC Chemist, put a label “Cleaned” or “Ready for use”.

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