Therapeutic
incompatibility
q Therapeutic Incompatibility may be a result of
prescribing certain drugs to a patient with the intention to produce a specific
degree of pharmacological action but the nature or intensity of the action
produced is different from that intended by the prescriber.
q This occurs due to the following reasons:-
q Error in dosage
q Wrong drug or dosage form
q Contra-indicated drugs
q Synergistic and antagonistic drugs
q Drug interactions
q Prescribing drugs with wrong direction.
Error in dosage
q Many therapeutic incompatibilities result from
errors in writing or interpreting the prescription order.
q The most serious type of dosage error in the
dispensing is overdose of the medication.
q It becomes the duty of the pharmacist to check
the prescription before dispensing.
q Pharmacist is often in the position to detect such errors and help to avoid such problems.
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